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UO > Research > Projects & Grants

Projects & Grants

Bone Marrow Microenvironment in Multiple Myeloma: Application of 2D and 3D in vitro models using patient's specific IPSCs derived Mesenchymal Stem cells
Project Id	MSK TO1_LF
Main solver	prof. MUDr. Roman Hájek, CSc.
Period	8/2016 - 12/2017
Provider	Katedra interních oborů, Projekty podporované z rozpočtu měst krajských úřadů
State	finished
Anotation	The current project builds on input project "Zahájení dlouhodobého výzkumu u monoklonálních gamapatií" and will promote further development of applied and basic research at the Medical Faculty, University of Ostrava. We proposed to establish ?myeloma-in-dish? 3D model together with application of Induced Pluripotent Stem Cells (iPSCs) technology. The aim is to generate in vitro bone marrow microenvironment model based on multiple components and growth factors in the presence of mesenchymal cell to explore new avenue towards the drug development.